Tropospheric ozone (O₃) is an important pollutant that can regulate the atmospheric oxidizing capacity and regional climate. O₃ deposition to the ocean surface accounts for approximately one-third of its global loss, making the ocean an important sink for tropospheric O₃. In most atmospheric chemistry and climate models, the dry deposition velocity of O₃ over the ocean is simplified as a constant value of in the range of 0.01–0.03 cm s⁻¹. Studies have shown that the deposition velocity is controlled by both chemical reactions between O₃ and seawater chemical compositions (i.e., iodine) and turbulent mixing in the surface ocean. However, the chemical reactions between O₃ and seawater surface remain unclear, particularly the role of iodine chemistry. Moreover, the observed O₃ dry deposition velocities vary by more than an order of magnitude and exhibit pronounced regional variability, with generally higher values in coastal regions and warmer waters. In this study, we utilized an air–sea interaction experimental chamber system to conduct laboratory simulations investigating the variability of O₃ deposition rates under diverse experimental conditions. We found that sea water chemical compositions such as iodide (I⁻), humic acid (HA), and chloride (Cl⁻) have significant effects on the O₃ deposition, with the deposition rates ranging from 0.022 to 0.076 cm s⁻¹. The presentation will also discuss the possible key regulating chemical mechanism of O₃ deposition on the sea surface in the marine atmosphere.